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2-Methyl-3-butyn-2-ol 2-甲基-3-丁炔-2-醇

规格: 98%
CAS: 115-19-5
产品编号: H91470
MDL: MFCD00004467
品牌: INFI
Chemical Name2-Methyl-3-butyn-2-ol
CAS Number115-19-5
Alfabeta NameMETHYLBUTYNOL 232-----
MDL NumberMFCD00004467
Synonym AB 32 (alcohol) alpha,alpha-Dimethylpropargyl alcohol 2-Methylbut-3-in-2-ol 3-METHYL-1-BUTYN-3-OL 2-Methyl-3-butyne-2-ol Dimethyl ethynyl carbinol; 2,2-Dimethylpropargyl alcohol 3-羥-3-甲-1-丁炔 1,1-dimethylpropargylalcohol {Chemicalbook} 1,1-dimethylpropynol 1,1-Dimethyl-2-propyn-1-ol 2-Hydroxy-2-methyl-3-butin 2-methylbut-3-yn-2-ol 3-Methyl-3-hydroxy-1-butyne 3-Butyn-2-ol, 2-methyl- Dimethylethynylmethanol {uni_hambur 3-Methylbut-1-yn-3-ol 2-甲基-3-丁炔-2-醇 Dimethyl ethynyl carbinol,2,2-Dimethylpropargyl alcohol Ethynyldimethylcarbinol 3-Methyl-butin-(1)-ol-(3) α,α-Dimethylpropargyl alcohol 3-Methyl-1-butyn-3-ol Ethinyl-dimethylca {C
EC Number204-070-5
Beilstein Registry Number1(1)235
PubChem Substance ID8258
Reaxys-RN635746
Merck Number6034
Chemical Name Translation2-Methyl-3-butyn-2-ol 2-甲基-3-丁炔-2-醇
Wiswesser Line NotationQX1&1&1UU1
LabNetwork Molecule IDLN00175014
InChIInChI=1S/C5H8O/c1-4-5(2,3)6/h1,6H,2-3H3
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 31(4),55,1987

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1161 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 76,181,1956

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2 gm/m3
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 31(4),55,1987

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1950 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than

Warnings 危化品目录(2015) IRRITANT
WGK Germany1
Hazard Codes
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H351 Suspected of causing cancer 怀疑致癌
  • H318 Causes serious eye damage 严重伤害眼睛
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H302 Harmful if swallowed 吞食有害
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
    Precautionary statements
    • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P305+P351+P338
    • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
    • P301+P312+P330
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P303+P361+P353
    • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
    • P370+P378
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
    • P403+P235
    • P304+
      Signal word
      Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
      Safety Statements
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
      • S36/39 Wear suitable protective clothing and eye/face protection 穿戴适当的防护服和眼睛/面保护;
      • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
      • S39 Wear eye/face protection 戴眼睛/面孔保护装置;
      • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
      • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
      • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
        Risk Statements
        • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
        • R10 Flammable 易燃
        • R22 Harmful if swallowed 吞咽有害
        • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
          RTECSES0810000
          UN Number 1987
          Packing GroupIII
          Hazard Class3
          Storage condition Flammables area
        • {ALF} Alternatively, the protecting group can be removed from the intermediate by base to give monoarylacetylenes: J. Org. Chem., 48, 5135 (1983); 57, 6998 (1992). For an improved procedure, see: Synthesis, 589 (1996).
        • {ALF} Adduct of acetylene and acetone which acts as an acetylene equivalent in the Pd-catalyzed (Sonogashira) coupling reaction with aryl or heteroaryl halides, permitting a one-pot diarylation by different halides: Synthesis, 571 (1984):
        • {uni_hamburg} Short: III/38B
        • {ALD} Merck:14,6034
        • {uni_hamburg} Short: IV/18B
        • {ALD} Merck:14,6034
        • Beilstein:1(1)235
        • 115-19-5 H91470 2-Methyl-3-butyn-2-ol
2-甲基-3-丁炔-2-醇

          化学属性

          Mol. FormulaC5H8O
          Mol. Weight84.12
          Density0.868
          Refractive index1.4200 to 1.4230
          Boiling Point103°C
          Melting Point2.6
          Flash Point22°(72°F)
          TSCAYes
          Autoignition Point662 °F
          Vapor Pressure15 mmHg ( 20 °C)
          Solubility与水混溶,可混溶于丙酮、苯、四氯化碳、石油醚。