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1,3-Dimethyl-2-imidazolidinone 1,3-二甲基-2-咪唑啉酮

规格: 98%
CAS: 80-73-9
产品编号: H86609
MDL: MFCD00003188
品牌: INFI
Chemical Name1,3-Dimethyl-2-imidazolidinone
Synonym N,N'-Dimethyl-2-imidazolidinone 1,3-DIMETHYLIMIDAZOLIDONE 二甲基咪唑烷酮 N,N'-Dimethylethyleneurea 1,3-DIMETHYLIMIDAZOLIDIN-2-ONE N,N′-二甲基亚乙基脲 DMEU DMI N,N'-Dimethyl-2-imidazolidinone rhonite1 {Chemicalb N,N'-DIMETHYLETHYLENEUREA Karbomos TsEM 1,3-Dimethylethyleneurea 1,3-Dimethyl-2-imidazolidone 1,3-二甲基咪唑啉酮 N,N’-二甲基亚乙基脲 1,3-二甲基咪唑酮 1,3-dimethyl-imidazolidin-2-one {uni_ham N,N′-二甲基亚乙基脲 DMEU 1,3-Dimethylimidazolidinone 1,3-二甲基-2-咪唑啉酮, 98% 1,3-dimethyl-2-imidazodinone NN'-Dimethylethyleneurea N,N′-Dimethylethyleneurea
MDL NumberMFCD00003188
CAS Number80-73-9
EC Number201-304-8
Beilstein Registry Number108808
PubChem Substance ID87567974
Merck Number3249
Chemical Name Translation1,3-二甲基-2-咪唑啉酮
Reaxys-RN108808
Wiswesser Line NotationT5NVNTJ A1 C1
LabNetwork Molecule IDLN00193489
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1190 uL/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - ptosis
   Behavioral - tremor
   Skin and Appendages - hair
REFERENCE :
   ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,
   Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128)  V.1-
   1990-  Volume(issue)/page/year: 1,191,1992

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2840 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 11,214,1968

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 930 uL/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Gastrointestinal - changes in structure or function of salivary glands
   Gastrointestinal - other changes
REFERENCE :
   ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,
   Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128)  V.1-
   1990-  Volume(issue)/page/year: 1,191,1992

Signal word
WGK Germany3
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
    Risk Statements
    • R62 Possible risk of impaired fertility 有削弱生殖能力的危险
    • R22 Harmful if swallowed 吞咽有害
    • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
    • R21/22 Harmful in contact with skin and if swallowed 皮肤接触和不慎吞咽有害
    • R38 Irritating to skin 刺激皮肤
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
    • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
      Precautionary statements
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P305+P351+P338
      • P332+P313
      • P302+P352+P312+P361+P364
      • P405 Store locked up. 上锁保管。
      • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
      • P305+P351+P338+P337+P313
        Hazard statements
        • H302 Harmful if swallowed 吞食有害
        • H315 Causes skin irritation 会刺激皮肤
        • H318 Causes serious eye damage 严重伤害眼睛
        • H311 Toxic in contact with skin 皮肤接触中毒
        • H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
        • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
          Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
          RTECSNJ0660000
          Packing GroupIII
          UN Number UN2810
          Storage condition Hygroscopic
          Hazard Codes Xn Xn,Xi
          Hazard Class6.1
        • DMI广泛应用于化工、医药、农药、染料等精细化学品的合成,同时应用于有机合成、高分子合成、高能电池的电解液、喷墨油墨、水基油墨、催化剂、药物增效剂、特种洗涤剂的添加剂。DMI在美国、西欧和日本在工业上用于化学药物,农用化学和精细化学品合成中的许多反应。
        • {ALD} Merck: 14,3249
        • Beilstein: 24,IV,9
        • {
        • {ALF} High-boiling polar aprotic solvent which has been recommended as a replacement for the carcinogenic hexamethylphosphoric triamide, HMPA. It is stable to alkali metals and strong bases: J. Organomet. Chem., 92, C46 (1975); 117, 149 (1976).
        • {uni_hamburg} Short: III/38B
        • {ALF} For example, it has been used as a solvent for the displacement of non-activated aryl halides by thiolates: Tetrahedron Lett., 23, 4131 (1982); J. Org. Chem., 44, 2642 (1979); 45, 4376 (1980); and as a superior solvent in the Ullmann aryl ether synthesis: Chem. Lett., 899 (1988).
        • {uni_hamburg} Short: IV/10A
        • {ALD} Merck: 14,3249
        • 80-73-9 H86609 1,3-Dimethyl-2-imidazolidinone	1,3-二甲基-2-咪唑啉酮

          化学属性

          Mol. FormulaC5H10N2O
          Mol. Weight114.15
          Density1.056
          Refractive index1.4710 to 1.4730
          Boiling Point224-226
          Flash Point120°C(lit.)
          TSCAYes
          Melting Point
          Solubility易溶