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1,3-Dimethyl-2-imidazolidinone 1,3-二甲基-2-咪唑啉酮

规格: 98%

CAS: 80-73-9

产品编号: H86609

MDL: MFCD00003188

品牌: INFI

Chemical Name	1,3-Dimethyl-2-imidazolidinone
Synonym	1,3-Dimethyl-2-imidazolidinone {LY} 1,3-Dimethyl-2-imidazolidinone {} {LY} 1,3-Dimethyl-2-imidazolidinone {} {} {LY} 1,3-Dimethyl-2-imidazolidinone {} {} {} {LY} 1,3-Dimethyl-2-imidazolidinone {} {} {} {} {LY} 1,3-Dimethyl-2-imidazolidinone {} {} {} {} {} {LY} 1,3-Dimethyl-2-imidazolidinone {} {} {} {} {} {} {LY} 1,3-Dimethyl-2-imidazolidinone {} {} {} {} {} {} {} {LY} 1,3-Dimethyl-2-imidazolidinone {} {} {} {} {} {} {} {} {LY} 1,3-Dimethyl-2-imidazolidinone {} {} {} {} {} {} {} {} {} {LY} 1,3-Dimethyl-2-imidazolidinone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,3-Dimethyl-2-imidazolidinone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,3-Dimethyl-2-imidazolidinone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,3-Dimethyl-2-imidazolidinone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,3-Dimethyl-2-imidazolidinone {} {} {} {} {} {} {} {} {} {
MDL Number	MFCD00003188
CAS Number	80-73-9
EC Number	201-304-8
Beilstein Registry Number	108808
PubChem Substance ID	87567974
Merck Number	3249
Chemical Name Translation	1,3-二甲基-2-咪唑啉酮
Reaxys-RN	108808
Wiswesser Line Notation	T5NVNTJ A1 C1
LabNetwork Molecule ID	LN00193489
Canonical SMILES	O=C1N(C)CCN1C

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1190 uL/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - ptosis
   Behavioral - tremor
   Skin and Appendages - hair
REFERENCE :
   ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,
   Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128)  V.1-
   1990-  Volume(issue)/page/year: 1,191,1992

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2840 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 11,214,1968

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 930 uL/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Gastrointestinal - changes in structure or function of salivary glands
   Gastrointestinal - other changes
REFERENCE :
   ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,
   Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128)  V.1-
   1990-  Volume(issue)/page/year: 1,191,1992

Signal word	Danger
WGK Germany	3
Safety Statements
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见； S36 Wear suitable protective clothing 穿戴适当的防护服； S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
Risk Statements
R21/22 Harmful in contact with skin and if swallowed 皮肤接触和不慎吞咽有害 R22 Harmful if swallowed 吞咽有害 R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性 R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性 R38 Irritating to skin 刺激皮肤 R41 Risk of serious damage to eyes 有严重损伤眼睛的危险 R62 Possible risk of impaired fertility 有削弱生殖能力的危险
Precautionary statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。 P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。 P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。 P302+P352+P312+P361+P364 P305+P351+P338 P305+P351+P338+P337+P313 P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。 P332+P313 P405 Store locked up. 上锁保管。 P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
H302 Harmful if swallowed 吞食有害 H315 Causes skin irritation 会刺激皮肤 H318 Causes serious eye damage 严重伤害眼睛 H311 Toxic in contact with skin 皮肤接触中毒 H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害 H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
Personal Protective Equipment	Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECS	NJ0660000
Packing Group	III
UN Number	2810 UN2810
Storage condition	Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Hazard Codes	6.1 Xn Xn,Xi
Hazard Class	6.1

DMI广泛应用于化工、医药、农药、染料等精细化学品的合成，同时应用于有机合成、高分子合成、高能电池的电解液、喷墨油墨、水基油墨、催化剂、药物增效剂、特种洗涤剂的添加剂。DMI在美国、西欧和日本在工业上用于化学药物，农用化学和精细化学品合成中的许多反应。

{ALD} Merck: 14,3249

Beilstein: 24,IV,9

{

{ALF} High-boiling polar aprotic solvent which has been recommended as a replacement for the carcinogenic hexamethylphosphoric triamide, HMPA. It is stable to alkali metals and strong bases: J. Organomet. Chem., 92, C46 (1975); 117, 149 (1976).

{uni_hamburg} Short: III/38B

{ALF} For example, it has been used as a solvent for the displacement of non-activated aryl halides by thiolates: Tetrahedron Lett., 23, 4131 (1982); J. Org. Chem., 44, 2642 (1979); 45, 4376 (1980); and as a superior solvent in the Ullmann aryl ether synthesis: Chem. Lett., 899 (1988).

{uni_hamburg} Short: IV/10A

{ALD} Merck: 14,3249

80-73-9 H86609 1,3-Dimethyl-2-imidazolidinone
1,3-二甲基-2-咪唑啉酮

化学属性

Mol. Formula	C5H10N2O
Mol. Weight	114.15
Density	1.056
Refractive index	1.4710 to 1.4730
Boiling Point	224-226°C at 760 mmHg
Flash Point	95°C
TSCA	Yes
Melting Point	7.5°C
Solubility	易溶

*以上化合物性质及应用等信息仅供参考

手性催化剂及配体

合成砌块

医药中间体

1,3-Dimethyl-2-imidazolidinone 1,3-二甲基-2-咪唑啉酮

规格: 98%

化学属性

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