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Ethynyltrimethylsilane 三甲基硅乙炔

规格: 97%

CAS: 1066-54-2

产品编号: H83632

MDL: MFCD00008569

品牌: INFI

Chemical Name	Ethynyltrimethylsilane
CAS Number	1066-54-2
Alfabeta Name	TRIMETHYLSILYLACETYLENE ()
MDL Number	MFCD00008569
Synonym	(Trimethylsilanyl)acetylene {LY} (Trimethylsilanyl)acetylene {} {LY} (Trimethylsilanyl)acetylene {} {} {LY} (Trimethylsilanyl)acetylene {} {} {} {LY} (Trimethylsilanyl)acetylene {} {} {} {} {LY} (Trimethylsilanyl)acetylene {} {} {} {} {} {LY} (Trimethylsilanyl)acetylene {} {} {} {} {} {} {LY} (Trimethylsilanyl)acetylene {} {} {} {} {} {} {} {LY} (Trimethylsilanyl)acetylene {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} (Trimethylsilanyl)acetylene {} {} {} {} {} {} {} {} {} {LY} (Trimethylsilanyl)acetylene {} {} {} {} {} {} {} {} {} {} {LY} (Trimethylsilanyl)acetylene {} {} {} {} {} {} {} {} {} {} {} {LY} (Trimethylsilanyl)acetylene {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} (Trimethylsilanyl)acetylene {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} (Trimethylsilanyl)acetylene {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} (Trimethylsilanyl)acetylene {} {} {} {} {} {} {} {} {} {} {} {
PubChem Substance ID	87577015
Beilstein Registry Number	906752
EC Number	213-919-9
Reaxys-RN	906752
Chemical Name Translation	三甲基乙炔基硅
InChIKey	CWMFRHBXRUITQE-UHFFFAOYSA-N
LabNetwork Molecule ID	LN00117256
InChI	InChI=1S/C5H10Si/c1-5-6(2,3)4/h1H,2-4H3
Canonical SMILES	C[Si](C)(C#C)C

GHS Symbol

Warnings	IRRITANT, KEEP COLD, FLAMMABLE
WGK Germany	3
Hazard statements
H225 Highly flammable liquid and vapour 高度易燃液体和蒸气 H315 Causes skin irritation 会刺激皮肤 H319 Causes serious eye irritation 严重刺激眼睛 H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment	Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US)
Hazard Codes	3 F;Xi
Precautionary statements
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。 P233 Keep container tightly closed. ?保持容器密闭。 P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。 P241+P242+P243 P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。 P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。 P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。 P302+P352+P332+P313+P362+P364 P303+P361+P353 P305+P351+P338 P305+P351+P338+P337+P313 P332+P313 P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用 P370+P378 P403+P235 P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word	Danger
Safety Statements
S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟； S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见； S29 Do not empty into drains 不要排入下水道； S33 Take precautionary measures against static discharges 对静电采取预防措施； S36 Wear suitable protective clothing 穿戴适当的防护服； S9 Keep container in a well-ventilated place 保持容器在通风良好的场所；
Risk Statements
R11 Highly flammable 非常易燃 R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
UN Number	1993 UN 1993 3/PG 2
Packing Group	II
Storage condition	2-8°C, protect from light, stored under nitrogen {LY} 2-8°C, protect from light, stored under nitrogen {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen
Hazard Class	3

Ethynyltrimethylsilane was used in:

? microwave-assisted, one-pot, three-step Sonogashira cross-coupling-desilylation-cycloaddition reaction for the preparation of 1,4-disubstituted 1,2,3-triazoles

synthesis of poly(ethynyltrimethylsilane) containing Pd (II) coordination sites

pyrazole synthesis via 1,3-dipolar cycloaddition of diazo compounds to acetylenes

{ALD} Beilstein: 4,IV,3937

{ALF} For the synthesis of iodoalkenes by radical addition of perfluoroalkyl iodides, see: J. Org. Chem., 47, 2251 (1982).

{uni_hamburg} Short: II/24A

{ALF} Pd catalyzed coupling with aryl bromides or iodides gives aryl TMS alkynes, from which the TMS group is readily cleaved by K2CO3 in MeOH: Synthesis, 627 (1980); J. Org. Chem., 46, 2280 (1981). Coupling with 1-bromo-2-nitrobenzene or ethyl 2-bromocarbanilate gives indole precursors. Other terminal alkynes lead to 2-substituted indoles: Heterocycles, 24, 31 (1986):

{ALF} Cross-coupling with aryl halides can also be catalyzed by Pd-C in the presence of Ph3P, CuI and Et3N: Synth. Commun., 20, 2059 (1990); for an example, see 2-Bromonaphthalene, A15300. Pd catalyzed coupling with quinolinol and isoquinolinol triflates has also been reported: Tetrahedron, 51, 3737 (1995). For coupling with vinyl halides catalyzed by Tetrakis(triphenylphosphine)palladium(0), 10548 in the presence of CuI as an example of a route to enynes, see: Tetrahedron Lett., 30, 6997 (1989); Org. Synth. Coll., 9, 117 (1998). CuCl-TMEDA catalyzed oxidative (Hay) coupling gives bis(TMS)-1,3-butadiyne: Org. Synth. Coll., 8, 63 (1993).

1066-54-2 H83632 Ethynyltrimethylsilane
三甲基硅乙炔

化学属性

Mol. Formula	C5H10Si
Mol. Weight	98.22
Boiling Point	52-53°C at 760 mmHg
TSCA	T
Refractive index	1.3890 to 1.3910
Density	0.695
Flash Point	-34°C
Vapor Pressure	4.18 psi ( 20 °C)
Solubility	起反应
Stability	对空气和湿度敏感
Melting Point	>0 °C
pH	:A

*以上化合物性质及应用等信息仅供参考

手性催化剂及配体

合成砌块

医药中间体

Ethynyltrimethylsilane 三甲基硅乙炔

规格: 97%

化学属性

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