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Cyclohexanone 环己酮

规格: 99%

CAS: 108-94-1

产品编号: H59213

MDL: MFCD00001625

品牌: INFI

Chemical Name	Cyclohexanone
CAS Number	108-94-1
EC Number	203-631-1
Beilstein Registry Number	7,8
MDL Number	MFCD00001625
Synonym	AKOS BBS-00004296 ANONE Anon Anone C₆H₁₀O (cyclohexanone) CYCLOHEXANONE Cicloesanone Cyclohexanon Cyclohexanone Cyclohexyl ketone Cykloheksanon FEMA 3909 HEXANONE Hexanon Hytrol O KETOCYCLOHEXANE KETOHEXAMETHYLENE Ketohexamethylene NCI-C55005 Nadone Oxocyclohexane PIMELIC KETONE Pimelic ketone Pimelin ketone RCRA waste number U057 Sextone caswellno270 cyclohexanone cykloheksanon(polish) epapesticidechemicalcode025902 hytrolo {} {} {} {} {} {} {} {} {} {uni_hamburg} 安酮环己酮
PubChem Substance ID	7967
Merck Number	2726
Reaxys-RN	385735
Chemical Name Translation	环己酮
Wiswesser Line Notation	L6VTJ
LabNetwork Molecule ID	LN00195875
InChI	InChI=1S/C6H10O/c7-6-4-2-1-3-5-6/h1-5H2

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1130 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - other changes
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   49,525,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1 mL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   30,470,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2170 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher information, see AEHLAU.
   Volume(issue)/page/year: 25,415,1943

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Mammal - specie

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 20 uL/L
REFERENCE :
   EJMBA2 Egyptian Journal of Microbiology.  (National Information and
   Documentation Centre, A1-Tahrir St., Awqaf P.O. Dokki, Cairo, Egypt)  V.7-
   1972-  Volume(issue)/page/year: 18,213,1983

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 7500 uL/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 7(Suppl
   3),60,1985

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Leukocyte
DOSE/DURATION           : 100 umol/L
REFERENCE :
   DBTEAD Diabete.  (Le Raincy, France)  V.1-22, 1953-74.  Discontinued.
   Volume(issue)/page/year: 19,215,1971

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 5 ug/L
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 46(5),76,1981

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 7500 uL/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 7(Suppl
   3),60,1985

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 200 uL/L
REFERENCE :
   EJMBA2 Egyptian Journal of Microbiology.  (National Information and
   Documentation Centre, A1-Tahrir St., Awqaf P.O. Dokki, Cairo, Egypt)  V.7-
   1972-  Volume(issue)/pag

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 11 gm/kg
SEX/DURATION            : female 8-12 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis.  (Alan R. Liss, Inc.,
   41 E. 11th St., New York, NY 10003)  V.1-    1980- Volume(issue)/page/year:
   6,361,1986

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 105 mg/m3/4H
SEX/DURATION            : female 1-20 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv.
   Toxicology of New Industrial Chemical Substances.  For English translation,
   see TNICS*.  (Izdatel'stvo Meditsina, Moscow, USSR)  No.1-    1961-
   Volume(issue)/page/year: 14,26,1975

Signal word
WGK Germany	1
Safety Statements
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见； S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
Risk Statements
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性 R10 Flammable 易燃 R20 Harmful by inhalation 吸入有害
Precautionary statements
P201 Obtain special instructions before use. 使用前获取专门指示。 P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。 P203 P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。 P233 Keep container tightly closed. ?保持容器密闭。 P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。 P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。 P241+P242+P243 P242 Use only non-sparking tools. 只能使用无火花工具。 P243 Take precautionary measures against static discharge. 采取预防措施，防止静电放电。 P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。 P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。 P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。 P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。 P264+P265 P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。 P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。 P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。 P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。 P281 Use personal protective equipment as required. 使用所需的个人防护装备。 P301+P310 P301+P310+P331+P330 P301+P312 P301+P316 P301+P317 P302 P302+P352 P302+P352+P312+P361+P364 P303+P361+P353 P304+P312 P304+P340 P305+P351+P338 P305+P351+P338+P337+P313 P305+P354+P338 P307+P311 P308+P311 P308+P313 P308+P316 P309+P311 P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。 P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。 P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。 P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医，如果你觉得不舒服 P316 P317 P318 P319 P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。 P322 Specific measures (see …on this label). 具体治疗（见本标签上的）。 P330 Rinse mouth. 漱口 P331 Do NOT induce vomiting.. 不要催吐。 P332+P313 P332+P317 P333+P313 P333+P317 P337+P313
Hazard statements
H226 Flammable liquid and vapour 易燃液体和蒸气 H302 Harmful if swallowed 吞食有害 H302+H312+H332 H312 Harmful in contact with skin 皮肤接触有害 H315 Causes skin irritation 会刺激皮肤 H318 Causes serious eye damage 严重伤害眼睛 H332 Harmful if inhaled 吸入有害
Personal Protective Equipment	Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECS	GW1050000
Packing Group	III
UN Number	1915
Hazard Codes
Storage condition	密封保存 Flammables area
Hazard Class	3
Warnings	危化品目录(2015)
Restrict	危险品

纤维、树脂、橡胶、石蜡、虫胶和DDT的溶剂，有机合成，能溶解许多由元素与有机试剂所形成的络合物，测定铋，萃取稀有金属铀、钍、钴和钛的试剂。

{uni_hamburg} Short: II/19c

{uni_hamburg} Short: II/19b

{ALD} Merck:14,2726

{uni_hamburg} Short: II/14a

{ALD} Merck:14,2726

Beilstein:7,8

化学属性

Mol. Formula	C6H10O
Mol. Weight	98
Density	0.947
Autoignition Point	788 °F
Refractive index	1.4490 to 1.4530
Vapor Density	3.4 (vs air)
Boiling Point	157°C
Vapor Pressure	3.4 mmHg ( 20 °C)
Melting Point	-47
Flash Point	44°C(lit.)
TSCA	Yes
Solubility	微溶于水，可混溶于醇、醚、苯、丙酮等多数有机溶剂。
Danger-Level	乙类

*以上化合物性质及应用等信息仅供参考

手性催化剂及配体

合成砌块

医药中间体

Cyclohexanone 环己酮

规格: 99%

化学属性

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