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Phloretin 根皮素

规格: 97%

CAS: 60-82-2

产品编号: H24360

MDL: MFCD00002288

品牌: INFI

Chemical Name	Phloretin
CAS Number	60-82-2
Alfabeta Name	TRIHYDROXYHYDROXYPHENYLPROPIOPHENONE 24634()-----,,'''
MDL Number	MFCD00002288
Synonym	3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone, 2',4',6'-Trihydroxy-3-(4-hydroxyphenyl)propiophenone β-(4-Hydroxyphenyl)-2,4,6-trihydroxypropiophenone, 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone, 2μ,4μ,6μ-Trihydroxy-3-(4-hydroxyphenyl)propiophenone 4,2',4',6'-TETRAHYDROXYDIHYDROCHALCONE 2',4',6'-TRIHYDROXY-3-(4-HYDROXYPHENYL)-PROPIOPHENONE β-(4-hydroxyphenyl)-2,4,6-trihydroxypropiophenone Phloretin,98% 2',4',6'-Trihydroxy-3-(4-Hydroxyphenyl)propiophenone 2',4',6'-Trihydroxy-3-(4-hydroxyphenyl)propiophenone PHLORETIN (NATURAL)
EC Number	200-488-7
Beilstein Registry Number	1887240
Merck Number	7326
PubChem Substance ID	4788
Chemical Name Translation	根皮素
Reaxys-RN	1887240
InChI	InChI=1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2
LabNetwork Molecule ID	LN00116889

GHS Symbol

Warnings	IRRITANT
Signal word
WGK Germany	3
Safety Statements
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见； S37 Wear suitable gloves 戴适当手套；
Risk Statements
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。 P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用 P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。 P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。 P305+P351+P338 P332+P313 P305+P351+P338+P337+P313 P302+P352+P332+P313+P362+P364
Personal Protective Equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Hazard Codes	Xi
Hazard statements
H315 Causes skin irritation 会刺激皮肤 H319 Causes serious eye irritation 严重刺激眼睛 H335 May cause respiratory irritation 可能导致呼吸道刺激
Storage condition	0-10 0-10°C 储存温度-20°C 储存温度 2-8°C 2-8°C

A calcium channel protein inhibitor.

{MCE} [2]. Luo H, et al. Phloretin induces apoptosis of BEL-7402 cells in vitro. Nan Fang Yi Ke Da Xue Xue Bao. 2008 Jul;28(7):1249-51.

{MCE} [3]. Huang WC, et al. Phloretin and phlorizin promote lipolysis and inhibit inflammation in mouse 3T3-L1 cells and in macrophage-adipocyte co-cultures.Mol Nutr Food Res. 2013 Oct;57(10):1803-13.

{MCE} [4]. Wang SP, et al. Potent Antiarthritic Properties of Phloretin in Murine Collagen-Induced Arthritis.Evid Based Complement Alternat Med. 2016;2016:9831263.

{TRC} ########

{MCE} [1]. Kasahara T, Kasahara M. Expression of the rat GLUT1 glucose transporter in the yeast Saccharomyces cerevisiae. Biochem J. 1996 Apr 1;315 ( Pt 1):177-82.

{MCE} [2]. Luo H, et al. Phloretin induces apoptosis of BEL-7402 cells in vitro. Nan Fang Yi Ke Da Xue Xue Bao. 2008 Jul;28(7):1249-51.

化学属性

Mol. Formula	C15H14O5
Mol. Weight	274
Melting Point	260-262
Density	1.422
TSCA	No
Solubility	Soluble in ethanol, methanol, acetone, hot glacial acetic acid, alkalies, benzene (sparingly soluble), chloroform (sparingly soluble), and DMSO. Insoluble in water, and ether.
Refractive index	1.573-1.575
Stability	对热和光线敏感

*以上化合物性质及应用等信息仅供参考

手性催化剂及配体

合成砌块

医药中间体

Phloretin 根皮素

规格: 97%

化学属性

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