Chemilly-天津启瑞生物科技有限公司

2-Butyne-1,4-diol 2-丁炔-1,4-二醇

规格: 98%

CAS: 110-65-6

产品编号: H14390

MDL: MFCD00002915

品牌: INFI

Chemical Name	2-Butyne-1,4-diol
CAS Number	110-65-6
PubChem Substance ID	87563749
EC Number	203-788-6
Beilstein Registry Number	1071237
MDL Number	MFCD00002915
Reaxys-RN	1071237
Synonym	1,4-Dihydroxy-2-butyne, 1,2-Dihydroxydimethylacetylene 2-Butin-1,4-diol 2-丁炔-1,4-二醇 Bis(hydroxymethyl)acetylene but-2-yne-1,4-diol
Chemical Name Translation	1,4-丁炔二醇
Wiswesser Line Notation	Q2UU2Q
LabNetwork Molecule ID	LN00193774
InChI	InChI=1S/C4H6O2/c5-3-1-2-4-6/h5-6H,3-4H2

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - respiratory stimulation
   Blood - other changes
REFERENCE :
   HYSAAV Hygiene and Sanitation (USSR).  English translation of GISAAA.
   (Springfield, VA)  1964-

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 105 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - respiratory stimulation
   Blood - other changes
REFERENCE :
   HYSAAV Hygiene and Sanitation (USSR).  English translation of GISAAA.
   (Springfield, VA)  1964-71. Discontinued.  Volume(issue)/page/year:
   33(1-3),41,1968

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 105 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - respiratory stimulation
   Blood - other changes
REFERENCE :
   HYSAAV Hygiene and Sanitation (USSR).  English translation of GISAAA.
   (Springfield, VA)  1964-71. Discontinued.  Volume(issue)/page/year:
   33(1-3),41,1968

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 52435 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 26,597,1974

WGK Germany	2
Hazard statements
H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤 H317 May cause an allergic skin reaction 可能导致皮肤过敏 H301+H331 H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官 H312 Harmful in contact with skin 皮肤接触有害 H301+H311+H331 H331 Toxic if inhaled 吸入中毒 H301 Toxic if swallowed 吞食有毒
Personal Protective Equipment	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Hazard Codes	6.1 T
RTECS	ES0525000
Precautionary statements
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。 P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。 P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。 P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。 P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。 P273 Avoid release to the environment. 避免释放到环境中。 P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。 P301+P310 P301+P330+P331+P310 P303+P361+P353 P303+P361+P353+P310+P363 P304+P340+P310 P304+P340+P311 P305+P351+P338 P305+P351+P338+P310 P308+P311 P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。 P403+P233 P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word	Danger
UN Number	2716
Storage condition	0-10 密闭贮存. 0-10°C 储存温度2-8℃,充氩保存
Safety Statements
S25 Avoid contact with eyes 避免眼睛接触； S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见； S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护； S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）； S46 If swallowed, seek medical advice immediately and show this container or label 食入时，立即求医并出示容器/标签；
Risk Statements
R21 Harmful in contact with skin 与皮肤接触有害 R23/25 Toxic by inhalation and if swallowed 吸入及吞食都有毒 R34 Causes burns 会导致灼伤 R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应 R48/22
Packing Group	III
Hazard Class	6.1
Warnings	危化品目录(2015)
Restrict	危险品

丁二烯合成的中间体，腐蚀抑制剂，电镀光亮剂，聚合催化剂，脱叶剂，氯烃稳定剂。

{ALD} Beilstein:1(1)261

{uni_hamburg} Short: II/27B

{ALF} Undergoes an interesting trans-addition reaction with Grignard reagents: Chem. Lett., 765 (1984):

{uni_hamburg} Short: III/38B

110-65-6 H14390 2-Butyne-1,4-diol
2-丁炔-1,4-二醇

化学属性

Mol. Formula	C4H6O2
Mol. Weight	86
Boiling Point	238
Melting Point	54-58
Flash Point	152°(305°F)
TSCA	Yes
Vapor Pressure	<;0.1 mmHg ( 55 °C)
Refractive index	1.480
Density	1.2
Solubility	易溶于水，易溶于甲醇、乙醇，不溶于乙醚、苯、氯仿。
Stability	对湿度敏感

*以上化合物性质及应用等信息仅供参考

手性催化剂及配体

合成砌块

医药中间体

2-Butyne-1,4-diol 2-丁炔-1,4-二醇

规格: 98%

化学属性

Contact Us