Chemilly-天津启瑞生物科技有限公司

Diisobutylaluminum hydride 二异丁基氢化铝

规格: 1.5 M solution in toluene, SpcSeal

CAS: 1191-15-7

产品编号: H13013

MDL: MFCD00008928

品牌: INFI

Chemical Name	Diisobutylaluminium hydride
CAS Number	1191-15-7
EC Number	214-729-9
Beilstein Registry Number	4123663
MDL Number	MFCD00008928
Synonym	氫化二異丁基鋁 DIBAL-H Al-Alchili 二异丁基氢化铝, 25%甲苯溶液 Aluminum, diisobutylhydro- DIISOBUTYLALUMINUM HYDRIDE Bis(isobutyl)hydroaluminum 二异丁基氢化铝, 20% (CA 1M) SOLN. IN TOLUENE 氢化二异丁基铝 hydrobis(2-methylpropyl)-aluminu hydrobis(2-methylpropyl)-Aluminum DIBAL-H;DIBAL Aluminum, hydrodiisobutyl- DIISOBUTYLALUMINIUM HYDRIDE Aluminum, hydrobis(2-methylpropyl)- DIBAH 二异丁基氢化铝溶液 Diisobutylhydroaluminum DIBAL-H DIBAL hydrobis(2-methylpropyl)aluminum 二异丁基氢化铝 DI-I-BUTYLALUMINUM HYDRIDE Diisobutylaluminum 二异丁基氢化铝, 1M SOLUTION IN HEXANE
PubChem Substance ID	24852856
Chemical Name Translation	二异丁基氢化铝
Wiswesser Line Notation	1Y1&1-AL-H1Y1&1

GHS Symbol

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 70 gm/m3/1H
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   MELAAD Medicina del Lavoro.  Industrial Medicine.  (Via S. Barnaba, 8, 20122
   Milan, Italy) V.16-    1925-  Volume(issue)/page/year: 57,188,1966

Signal word	Danger
WGK Germany	2
Safety Statements
S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟； S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见； S27 Take off immediately all contaminated clothing 立即脱掉全部污染的衣服； S29 Do not empty into drains 不要排入下水道； S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护； S43 In case of fire use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add -?Never use water) 着火时使用（指明具体的消防器材种类，如果用水增加危险，注明“禁止用水” S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）； S46 If swallowed, seek medical advice immediately and show this container or label 食入时，立即求医并出示容器/标签； S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书； S62 If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label where possible 吞食后不要催吐：立即求医并出示该容器或标签； S7/8 Keep container tightly closed and dry 保存在严格密闭容器中，保持干燥； S9 Keep container in a well-ventilated place 保持容器在通风良好的场所；
Risk Statements
R11 Highly flammable 非常易燃 R14 Reacts violently with water 遇水会猛烈反应 R14/15 Reacts violently with water, liberating extremely flammable gases 遇水剧烈反应，释放出高度可燃气体 R17 Spontaneously flammable in air 在空气中能够自燃 R19 May form explosive peroxides 可能生成易爆的过氧化物质 R34 Causes burns 会导致灼伤 R35 Causes severe burns 会导致严重灼伤 R37 Irritating to respiratory system 刺激呼吸道 R48/20 R51/53 R62 Possible risk of impaired fertility 有削弱生殖能力的危险 R63 Possible risk of harm to the unborn child 可能危害未出生婴儿 R65 Harmful: may cause lung damage if swallowed 若吞咽可能伤害肺部器官 R67 Vapours may cause drowsiness and dizziness 蒸汽可能导致嗜睡和昏厥
Precautionary statements
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。 P231+P232 P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。 P273 Avoid release to the environment. 避免释放到环境中。 P422 Store contents under… 存储目录在…之下。
Hazard statements
H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤 H304 May be fatal if swallowed and enters airways 吞食和进入呼吸道可能致命 H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕 H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。 H261 In contact with water releases flammable gas 与水接触时释放可燃气体。 H225 Highly flammable liquid and vapour 高度易燃液体和蒸气 H250 Catches fire spontaneously if exposed to air 暴露于空气自发着火 H335 May cause respiratory irritation 可能导致呼吸道刺激 H351 Suspected of causing cancer 怀疑致癌 H260 In contact with water releases flammable gases which may ignite spontaneously 与水接触时释放可燃气体，可自燃。 H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官 H361d Suspected of damaging the unborn child 怀疑对未出生婴儿造成伤害 H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。 H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
Personal Protective Equipment	Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US) Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Packing Group	I
UN Number	3399
Storage condition	Moisture Sensitive 易吸潮，密封充氩保存 Air & Moisture Sensitive 充氩保存 2-8°C
RTECS	BD0710000
Hazard Codes	4.3 F,C
Hazard Class	4.3
Warnings	危化品目录(2015)
Restrict	危险品

⑴.无色液体，高度易燃。引起严重灼伤。吞食可能造成肺部损伤。蒸汽可能引起困倦和眩晕。

⑵.主要用作精细化学品的还原剂和氢铝化剂。

⑶.具有强烈的吸湿性，对空气和湿气敏感，遇水会发生激烈反应放出氢气。

⑷.四氢呋喃不适宜作溶剂，因为两者反应生成配位化合物。二异丁基氢化铝是一种新型金属有机化合物，可使酮、羧酸、酯选择性还原成相应的醛或者醇。

Used in Pd-catalyzed reductive debromination of secondary alkyl bromides. O-Debenzylation and ring opening of perbenzylated furanosides. Convenient in situ generation of HZrCp2Cl from ZrCp2Cl2 and DIBAL-H.

{ALD} Merck: 14,10425

{ALF} Reduces chiral ɑ-silyloxy esters to the corresponding enantiomerically-pure hydroxy aldehydes: J. Chem. Soc., Chem. Commun., 2475 (1995).

{ALD} Merck: 14,10425

Beilstein:4(4)4400

1191-15-7 H13013 Diisobutylaluminum hydride
二异丁基氢化铝

化学属性

Mol. Formula	C8H19Al
Mol. Weight	142.22
Density	0.84
TSCA	Yes
Flash Point	40 °F
Boiling Point	65 °C
Melting Point	-67 - -73 °C
Solubility	剧烈反应
Stability	易吸潮
pH	-:A
Danger-Level	-
Redox	-

*以上化合物性质及应用等信息仅供参考

手性催化剂及配体

合成砌块

医药中间体

Diisobutylaluminum hydride 二异丁基氢化铝

规格: 1.5 M solution in toluene, SpcSeal

化学属性

Contact Us